Dehydrated Human Amnion Chorion Membrane in Colorectal Anastomoses: A Retrospective Multi-Center Study

PURION® Processed Dehydrated Human Amnion/Chorion Membrane Allografts

Dehydrated Human Amnion/Chorion Membrane (dHACM) Allografts as a Therapy for Orthopedic Tissue Repair

The amniotic membrane is a placental tissue that supports the development of the fetus during pregnancy. It is composed of extracellular matrix components such as collagen, fibronectin, and laminin, and contains many different growth factors and cytokines. Amniotic membrane can be PURION Processed to produce dehydrated human amnion/chorion membrane (dHACM, Epifix, Amniofix; MiMedx Group Inc.) a...

Dehydrated human amnion/chorion membrane regulates stem cell activity in vitro

Human-derived placental tissues have been shown in randomized clinical trials to be effective for healing chronic wounds, and have also demonstrated the ability to recruit stem cells to the wound site in vitro and in vivo. In this study, PURION(®) Processed dehydrated human amnion/chorion membrane allografts (dHACM, EpiFix(®) , MiMedx Group, Marietta, GA) were evaluated for their ability to alt...

Identification of Extracellular Matrix Components and Biological Factors in Micronized Dehydrated Human Amnion/Chorion Membrane

Objective: The use of bioactive extracellular matrix (ECM) grafts such as amniotic membranes is an attractive treatment option for enhancing wound repair. In this study, the concentrations, activity, and distribution of matrix components, growth factors, proteases, and inhibitors were evaluated in PURION® Processed, micronized, dehydrated human amnion/chorion membrane (dHACM; MiMedx Group, Inc....

Dehydrated Human Amnion/Chorion Membrane Allograft Promotes Cardiac Repair Following Myocardial Infarctions

Acute myocardial infarction (MI), more commonly known as heart attack, is a major consequence of cardiovascular disease and a leading cause of morbidity and mortality worldwide. Acute MI occurs when coronary occlusion causes diminished blood supply to the cardiac tissue, and myocardial ischemia results in irreversible damage or cell death [1]. Reperfusion therapy in the form of primary percutan...